Amps not sure if this will exactly answer your question, so let me know if it doesn’t.
my workflow is to do initial sound design in session view, then once i have enough sounds that fit together to create the foundation for a track, i put together a skeleton arrangement (in arrangement view), and then do all future editing in arrangement unless i need a new sound. in that case, i go back to session view, create the new sound, paste it into the arrangement, rinse and repeat.
i’ve tried several different ways of arranging, but simple left to right chronological order works best for me. i find it easier to conceptualize the track and keep in moving toward the sound i’m looking for that way, plus it helps place fills/risers/transitions for me (as a side note, i usually create all my transitions by resampling existing sounds, i find everything sounds really glued together that way).
specific to your question, once you’ve edited it in arrangement, the clip in session view is essentially separate. i like that as it allows me to create a base, dry sound, then use arrangement view to add pattern variations, automation, etc.